How to breed more intelligent humans? This is a difficult question, one which raises numerous questions both ethical and scientific. Would you give your eyesight away to become brighter? As crazy as this question may sound, a blinding mutation might increase intelligence.
The CORD7 (cone-rod dystrophy 7) mutation of the RIMS1 gene produces progressive blindness in humans, and a previous study found that people carrying this mutation showed increased intelligence, particularly in childhood.
If you want to learn more, check MappingIgnorance.org