Spaceflight is known to affect human physiology, but the molecular mechanisms driving these changes to our bodies in space, like for instance, the loss of muscular mass, are yet unknown.
A recent study in the journal Cell used a multi-omics approach to try and examine these mechanisms. The researchers employed data from NASA’s GeneLab and NASA’s Twin Study. In total they gathered information from 59 astronauts and other samples flown in space, including human cell models, mouse strains, and mouse and human tissues. As an omics study, it aimed to assess transcriptomic, proteomic, metabolomic and epigenetic changes in response to spaceflight.
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