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A pinch of salt for CRISPR research

CRISPR-Cas9 editing of the genome
CRISPR-Cas9 editing of the genome. Credit: Ernesto del Aguila III, National Human Genome Research Institute, National Institutes of Health

Unless you’ve been sitting in a cave for the last couple of years, you have probably heard about the new great promise of gene therapy: the gene editing CRISPR system. This new addition to the molecular biology toolbox is groundbreaking for what it implies. It does not simply “force in” a healthy copy of whichever mutated version of a gene, but operates over the “sick” copy of the gen in the cell by cutting and replacing the mutated nucleotides for the “healthy” ones.  One of the big advantages of this method is that it avoids integration of extraneous DNA in regions away from the mutation, and there decreasing the chances of inducing tumoral processes.

 

If you wanna know more, keep on reading this article on MappingIgnorance

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